Search on: CDKN1C PROTEIN 
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Descriptor English:   Cyclin-Dependent Kinase Inhibitor p57 
Descriptor Spanish:   Inhibidor p57 de las Quinasas Dependientes de la Ciclina 
Descriptor Portuguese:   Inibidor de Quinase Dependente de Ciclina p57 
Synonyms English:   CDKN1C Protein
Cyclin Kinase Inhibitor Protein 2
Cyclin-Dependent Kinase Inhibitor 1C
p57 KIP2 Protein
p57KIP2 Protein
Cyclin Dependent Kinase Inhibitor 1C
Cyclin Dependent Kinase Inhibitor p57
KIP2 Protein, p57  
Tree Number:   D12.644.360.225.700
D12.776.167.187.700
D12.776.476.225.700
D12.776.624.776.355.700
Definition English:   A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expression of p57 is associated with various NEOPLASMS as well as with BECKWITH-WIEDEMANN SYNDROME. 
Pharmacological Action:   Protein Kinase Inhibitors
 
History Note English:   2006(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50933 
Unique Identifier:   D050761 

Occurrence in VHL:
 

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